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Necro Mastery - Slay the Spire 2 Card

Necro Mastery

NecrobinderPowerRare
2
Cost
Self
Target

Description

Summon 5. Whenever Osty loses HP, ALL enemies lose that much HP as well.

Keywords & Mechanics

SummonSelf-Damage

Synergizes With

Cards that work well with Necro Mastery based on shared mechanics and keyword interactions.

Strong Synergies

Afterlife

Afterlife

Skill · Common

Necro Mastery provides Summon → Afterlife benefits

Bodyguard

Bodyguard

Skill · Basic

Necro Mastery provides Summon → Bodyguard benefits

Cleanse

Cleanse

Skill · Uncommon

Necro Mastery provides Summon → Cleanse benefits

Devour Life

Devour Life

Power · Rare

Necro Mastery provides Summon → Devour Life benefits

Dirge

Dirge

Skill · Uncommon

Necro Mastery provides Summon → Dirge benefits

Invoke

Invoke

Skill · Common

Necro Mastery provides Summon → Invoke benefits

Good Synergies

Sleight of Flesh

Sleight of Flesh

Sleight of Flesh provides Self-Damage → Necro Mastery benefits

Card ID: NECRO_MASTERY

Character

Necrobinder

View all cards

Details

Rarity
Rare
Type
Power
Cost
2

Top Synergies

Afterlife — Skill card in Slay the Spire 2

Afterlife

Skill · ★★★

Bodyguard — Skill card in Slay the Spire 2

Bodyguard

Skill · ★★★

Cleanse — Skill card in Slay the Spire 2

Cleanse

Skill · ★★★

Devour Life — Power card in Slay the Spire 2

Devour Life

Power · ★★★

Dirge — Skill card in Slay the Spire 2

Dirge

Skill · ★★★

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Database last updated: March 2026