Home/Synergies

Card Synergy Browser

Every card in Slay the Spire 2 fits into one or more synergy mechanics. Pick a mechanic below to see which cards are enablers (set up the effect) and which are payoffs (reward you for building around it).

16Synergy Mechanics

548Cards Analysed

5Characters

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Debuffs

Vulnerable

22 cards

Vulnerable makes enemies take 50% more damage from attacks

Ironclad 11Silent 2Defect 1Necrobinder 3Regent 4

Weak

15 cards

Weak causes enemies to deal 25% less damage

Ironclad 2Silent 5Defect 3Necrobinder 3Regent 6

Poison

11 cards

Poison deals damage at the start of enemy turns

Silent 11

Buffs

Strength

37 cards

Strength adds extra damage to every attack

Ironclad 14Silent 6Defect 6Necrobinder 4Regent 10

Dexterity

85 cards

Dexterity adds extra Block to every block-granting card

Ironclad 23Silent 25Defect 23Necrobinder 21Regent 22

Block Build

32 cards

Big block cards and cards that scale with your Block

Ironclad 17Silent 12Defect 13Necrobinder 11Regent 14

Card Manipulation

Card Draw

78 cards

Draw extra cards for more options each turn

Ironclad 21Silent 23Defect 22Necrobinder 21Regent 21

Exhaust

36 cards

Cards that exhaust other cards, and cards that benefit when something is exhausted

Ironclad 18Defect 6Necrobinder 10Regent 2

Discard

21 cards

Discard synergies benefit from throwing away cards

Silent 20Defect 1

Retain

16 cards

Retained cards stay in your hand between turns

Ironclad 4Silent 7Defect 4Necrobinder 10Regent 5

Resources

Energy

56 cards

Extra energy lets you play more cards per turn

Ironclad 15Silent 18Defect 18Necrobinder 17Regent 14

Orbs (Defect)

Orbs

34 cards

Channel and amplify orbs (Lightning, Frost, Dark, Plasma)

Defect 34

Summons (Necrobinder)

Summon

30 cards

Summon and benefit from minions (Osty)

Ironclad 1Necrobinder 25Regent 3

Other

Self-Damage

14 cards

Cards that lose HP, and cards that scale or trigger from HP loss

Ironclad 13Necrobinder 1

Ethereal

23 cards

Ethereal cards exhaust if not played by end of turn

Defect 1Necrobinder 18Regent 2

Status Cards

9 cards

Create or benefit from status cards (Wound, Burn, Dazed, Void)

Defect 9

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